Properties and Mechanisms of Deletions, Insertions, and Substitutions in the Evolutionary History of SARS-CoV-2

Properties and Mechanisms of Deletions, Insertions, and Substitutions in the Evolutionary History of SARS-CoV-2

SARS-CoV-2 has accumulated many mutations since its emergence in late 2019. Nucleotide substitutions leading to amino acid replacements constitute the primary material for natural selection. Insertions, deletions, and substitutions appear to be critical for coronavirus’s macro- and microevolution. U...

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Bibliographic Details
Main Authors: Igor B. Rogozin, Andreu Saura, Eugenia Poliakov, Anastassia Bykova, Abiel Roche-Lima, Youri I. Pavlov, Vyacheslav Yurchenko
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:International Journal of Molecular Sciences
Subjects:
SARS-CoV-2
epistasis
mutation hotspots
ADAR
APOBEC
oxidative stress
Online Access:https://www.mdpi.com/1422-0067/25/7/3696

Internet

https://www.mdpi.com/1422-0067/25/7/3696

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