High-throughput sequencing unravels the cell heterogeneity of cerebrospinal fluid in the bacterial meningitis of children

High-throughput sequencing unravels the cell heterogeneity of cerebrospinal fluid in the bacterial meningitis of children

Bacterial meningitis (BM) is a common life-threatening infection in children that occurs in the central nervous system (CNS). The cytologic examination of cerebrospinal fluid (CSF) is a key parameter in the diagnosis of BM, but the heterogeneity of cells in the CSF has not been elucidated, which lim...

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Bibliographic Details
Main Authors: Haihan Xiao, Haijuan Xiao, Yun Zhang, Lingyun Guo, Zhenzhen Dou, Linlin Liu, Liang Zhu, Wenya Feng, Bing Liu, Bing Hu, Tianming Chen, Gang Liu, Tingyi Wen
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Immunology
Subjects:
bacterial meningitis
cerebrospinal fluid - CSF
cell heterogeneity
neuroinflammation
single-cell RNA sequencing (scRNA-seq)
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.872832/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2022.872832/full

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