Phylogeny-guided microbiome OTU-specific association test (POST)

Phylogeny-guided microbiome OTU-specific association test (POST)

Abstract Background The relationship between host conditions and microbiome profiles, typically characterized by operational taxonomic units (OTUs), contains important information about the microbial role in human health. Traditional association testing frameworks are challenged by the high dimensio...

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Bibliographic Details
Main Authors: Caizhi Huang, Benjamin J. Callahan, Michael C. Wu, Shannon T. Holloway, Hayden Brochu, Wenbin Lu, Xinxia Peng, Jung-Ying Tzeng
Format: Article
Language:English
Published: BMC 2022-06-01
Series:Microbiome
Subjects:
Association test
Phylogenetic tree
Kernel machine regression
Online Access:https://doi.org/10.1186/s40168-022-01266-3

Internet

https://doi.org/10.1186/s40168-022-01266-3

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