Protective effect of spore oil-functionalized nano-selenium system on cisplatin-induced nephrotoxicity by regulating oxidative stress-mediated pathways and activating immune response

Abstract In clinical practice, cisplatin is the most commonly used chemotherapy drug to treat a range of malignancies. Severe ROS-regulated nephrotoxicity, however, restricts its applicability. Currently, the main mechanisms leading to cisplatin-induced nephrotoxicity in clinical settings involve hy...

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Bibliographic Details
Main Authors: Chaofan Liu, Sajin Zhou, Haoqiang Lai, Lei Shi, Weibin Bai, Xiaoling Li
Format: Article
Language:English
Published: BMC 2023-02-01
Series:Journal of Nanobiotechnology
Online Access:https://doi.org/10.1186/s12951-022-01754-6