mTORC1 Controls Synthesis of Its Activator GTP

In this issue of Cell Reports, Emmanuel et al. (2017) report that mTORC1 activity is regulated by purine availability. This increases the number of mTORC1 regulators to include metabolites whose synthesis mTORC1 controls.

Bibliographic Details
Main Authors: Don Benjamin, Michael N. Hall
Format: Article
Language:English
Published: Elsevier 2017-06-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S221112471730846X