LncAABR07053481 inhibits bone marrow mesenchymal stem cell apoptosis and promotes repair following steroid-induced avascular necrosis

Long non-coding RNA AABR07053481 is shown to inhibit hypoxia-induced apoptosis of bone marrow mesenchymal stem cells in rats by regulating the miR-664-2-5p/Notch1 pathway, promote the repair efficacy of BMSCs on early steroid-induced avascular necrosis of the femoral head.

Bibliographic Details
Main Authors: Tao Wang, Zhi-Hong Xie, Lei Wang, Hong Luo, Jian Zhang, Wen-Tao Dong, Xiao-Han Zheng, Chuan Ye, Xiao-Bin Tian, Gang Liu, Xue-Song Zhu, Yan-Lin Li, Qing-Lin Kang, Fei Zhang, Wu-Xun Peng
Format: Article
Language:English
Published: Nature Portfolio 2023-04-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-023-04661-0