LncAABR07053481 inhibits bone marrow mesenchymal stem cell apoptosis and promotes repair following steroid-induced avascular necrosis
Long non-coding RNA AABR07053481 is shown to inhibit hypoxia-induced apoptosis of bone marrow mesenchymal stem cells in rats by regulating the miR-664-2-5p/Notch1 pathway, promote the repair efficacy of BMSCs on early steroid-induced avascular necrosis of the femoral head.
| Main Authors: | , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2023-04-01
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| Series: | Communications Biology |
| Online Access: | https://doi.org/10.1038/s42003-023-04661-0 |
| _version_ | 1797849923439296512 |
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| author | Tao Wang Zhi-Hong Xie Lei Wang Hong Luo Jian Zhang Wen-Tao Dong Xiao-Han Zheng Chuan Ye Xiao-Bin Tian Gang Liu Xue-Song Zhu Yan-Lin Li Qing-Lin Kang Fei Zhang Wu-Xun Peng |
| author_facet | Tao Wang Zhi-Hong Xie Lei Wang Hong Luo Jian Zhang Wen-Tao Dong Xiao-Han Zheng Chuan Ye Xiao-Bin Tian Gang Liu Xue-Song Zhu Yan-Lin Li Qing-Lin Kang Fei Zhang Wu-Xun Peng |
| author_sort | Tao Wang |
| collection | DOAJ |
| description | Long non-coding RNA AABR07053481 is shown to inhibit hypoxia-induced apoptosis of bone marrow mesenchymal stem cells in rats by regulating the miR-664-2-5p/Notch1 pathway, promote the repair efficacy of BMSCs on early steroid-induced avascular necrosis of the femoral head. |
| first_indexed | 2024-04-09T18:52:01Z |
| format | Article |
| id | doaj.art-bcefe4359b9f4098b43b9646079f2d19 |
| institution | Directory Open Access Journal |
| issn | 2399-3642 |
| language | English |
| last_indexed | 2024-04-09T18:52:01Z |
| publishDate | 2023-04-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Communications Biology |
| spelling | doaj.art-bcefe4359b9f4098b43b9646079f2d192023-04-09T11:24:43ZengNature PortfolioCommunications Biology2399-36422023-04-016111410.1038/s42003-023-04661-0LncAABR07053481 inhibits bone marrow mesenchymal stem cell apoptosis and promotes repair following steroid-induced avascular necrosisTao Wang0Zhi-Hong Xie1Lei Wang2Hong Luo3Jian Zhang4Wen-Tao Dong5Xiao-Han Zheng6Chuan Ye7Xiao-Bin Tian8Gang Liu9Xue-Song Zhu10Yan-Lin Li11Qing-Lin Kang12Fei Zhang13Wu-Xun Peng14Department of Orthopedics and Traumatology, The Affliated Hospital of Guizhou Medical UniversitySchool of Clinical Medicine, Guizhou Medical UniversityDepartment of Orthopedics and Traumatology, The Affliated Hospital of Guizhou Medical UniversitySchool of Clinical Medicine, Guizhou Medical UniversityDepartment of Orthopedics and Traumatology, The Affliated Hospital of Guizhou Medical UniversityDepartment of Orthopedics and Traumatology, The Affliated Hospital of Guizhou Medical UniversityDepartment of Orthopedics and Traumatology, The Affliated Hospital of Guizhou Medical UniversityDepartment of Orthopedics and Traumatology, The Affliated Hospital of Guizhou Medical UniversityDepartment of Orthopedics and Traumatology, The Affliated Hospital of Guizhou Medical UniversityDepartment of Orthopedics and Traumatology, The Affliated Hospital of Guizhou Medical UniversityDepartment of Orthopedic Surgery, The First Affiliated Hospital of Soochow UniversityDepartment of Sports Medicine, First Affiliated Hospital of Kunming Medical UniversityDepartment of Orthopedics, Shanghai Jiao Tong University Affiliated Sixth People’s HospitalDepartment of Orthopedics and Traumatology, The Affliated Hospital of Guizhou Medical UniversityDepartment of Orthopedics and Traumatology, The Affliated Hospital of Guizhou Medical UniversityLong non-coding RNA AABR07053481 is shown to inhibit hypoxia-induced apoptosis of bone marrow mesenchymal stem cells in rats by regulating the miR-664-2-5p/Notch1 pathway, promote the repair efficacy of BMSCs on early steroid-induced avascular necrosis of the femoral head.https://doi.org/10.1038/s42003-023-04661-0 |
| spellingShingle | Tao Wang Zhi-Hong Xie Lei Wang Hong Luo Jian Zhang Wen-Tao Dong Xiao-Han Zheng Chuan Ye Xiao-Bin Tian Gang Liu Xue-Song Zhu Yan-Lin Li Qing-Lin Kang Fei Zhang Wu-Xun Peng LncAABR07053481 inhibits bone marrow mesenchymal stem cell apoptosis and promotes repair following steroid-induced avascular necrosis Communications Biology |
| title | LncAABR07053481 inhibits bone marrow mesenchymal stem cell apoptosis and promotes repair following steroid-induced avascular necrosis |
| title_full | LncAABR07053481 inhibits bone marrow mesenchymal stem cell apoptosis and promotes repair following steroid-induced avascular necrosis |
| title_fullStr | LncAABR07053481 inhibits bone marrow mesenchymal stem cell apoptosis and promotes repair following steroid-induced avascular necrosis |
| title_full_unstemmed | LncAABR07053481 inhibits bone marrow mesenchymal stem cell apoptosis and promotes repair following steroid-induced avascular necrosis |
| title_short | LncAABR07053481 inhibits bone marrow mesenchymal stem cell apoptosis and promotes repair following steroid-induced avascular necrosis |
| title_sort | lncaabr07053481 inhibits bone marrow mesenchymal stem cell apoptosis and promotes repair following steroid induced avascular necrosis |
| url | https://doi.org/10.1038/s42003-023-04661-0 |
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