High Positive Predictive Value of Multitarget Stool DNA After Aerodigestive Tract Radiotherapy

High Positive Predictive Value of Multitarget Stool DNA After Aerodigestive Tract Radiotherapy

Background and Aims: Multitarget stool DNA (mt-sDNA) is approved for average-risk colorectal cancer screening; test performance in persons with prior radiation therapy (RT) has not been studied. RT can induce gastrointestinal bleeding and alter DNA methylation, which may affect mt-sDNA accuracy. Amo...

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Bibliographic Details
Main Authors: Derek W. Ebner, Jason D. Eckmann, Kelli N. Burger, Douglas W. Mahoney, Thomas J. Whitaker, Ivy A. Petersen, John B. Kisiel
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Gastro Hep Advances
Subjects:
Colorectal Cancer/Prevention and Control
Radiotherapy/Complications
Survivorship
DNA Neoplasm
Online Access:http://www.sciencedirect.com/science/article/pii/S2772572322000802

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http://www.sciencedirect.com/science/article/pii/S2772572322000802

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