Long Non-Coding RNA <i>H19</i> Prevents Lens Fibrosis through Maintaining Lens Epithelial Cell Phenotypes

Long Non-Coding RNA <i>H19</i> Prevents Lens Fibrosis through Maintaining Lens Epithelial Cell Phenotypes

The integrity of lens epithelial cells (LECs) lays the foundation for lens function and transparency. By contrast, epithelial-mesenchymal transition (EMT) of LECs leads to lens fibrosis, such as anterior subcapsular cataracts (ASC) and fibrotic forms of posterior capsule opacification (PCO). However...

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Bibliographic Details
Main Authors: Lang Xiong, Yan Sun, Jingqi Huang, Pengjuan Ma, Xiaoran Wang, Jiani Wang, Baoxin Chen, Jieping Chen, Mi Huang, Shan Huang, Yizhi Liu
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Cells
Subjects:
long non-coding RNA <i>H19</i>
lens fibrosis
epithelial-mesenchymal transition
TGF-β2
Smad-dependent signaling
Online Access:https://www.mdpi.com/2073-4409/11/16/2559

Internet

https://www.mdpi.com/2073-4409/11/16/2559

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