The establishment and application of MOG-IgG-mediated complement-dependent in vitro demyelination model

Objective To explore the pathogenic mechanism of myelin oligodendrocyte glycoprotein-IgG(MOG-IgG)associated disorders (MOGAD) and screen the treatment drugs by establishing the MOGAD in vitro demyelination model. Methods The patient-derived MOG-IgG was purified by using the affinity chromatography b...

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Bibliographic Details
Main Author: Chen Yashuang, Xiao Xiuqing, Wang Shisi, Mo Yongxin, Sun Xiaobo, Zhong Xiaofen, Peng Lisheng
Format: Article
Language:zho
Published: Editorial Office of Journal of New Medicine 2022-03-01
Series:Xin yixue
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Online Access:https://www.xinyixue.cn/fileup/0253-9802/PDF/1648889415911-1389411595.pdf