Characterization of Adenovirus 5 E1A Exon 1 Deletion Mutants in the Viral Replicative Cycle

Human adenovirus infection is driven by Early region 1A (E1A) proteins, which are the first proteins expressed following the delivery of the viral genome to the cellular nucleus. E1A is responsible for reprogramming the infected cell to support virus replication alongside the activation of expressio...

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Bibliographic Details
Main Authors: Rita Costa, Nikolas Akkerman, Drayson Graves, Leandro Crisostomo, Scott Bachus, Peter Pelka
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/12/2/213