Combining Hypermethylated <i>RASSF1A</i> Detection Using ddPCR with miR-371a-3p Testing: An Improved Panel of Liquid Biopsy Biomarkers for Testicular Germ Cell Tumor Patients

Combining Hypermethylated <i>RASSF1A</i> Detection Using ddPCR with miR-371a-3p Testing: An Improved Panel of Liquid Biopsy Biomarkers for Testicular Germ Cell Tumor Patients

The classical serum tumor markers used routinely in the management of testicular germ cell tumor (TGCT) patients—alpha fetoprotein (AFP) and human chorionic gonadotropin (HCG)—show important limitations. miR-371a-3p is the most recent promising biomarker for TGCTs, but it is not sufficiently informa...

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Bibliographic Details
Main Authors: João Lobo, Lieke M. J. van Zogchel, Mohammed G. Nuru, Ad J. M. Gillis, C. Ellen van der Schoot, Godelieve A. M. Tytgat, Leendert H. J. Looijenga
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Cancers
Subjects:
germ cell tumors
droplet digital PCR
microRNAs
methylation
biomarkers
miR-371a-3p
Online Access:https://www.mdpi.com/2072-6694/13/20/5228

Internet

https://www.mdpi.com/2072-6694/13/20/5228

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