Modulation of the Epithelial-Immune Cell Crosstalk and Related Galectin Secretion by DP3-5 Galacto-Oligosaccharides and β-3′Galactosyllactose

Modulation of the Epithelial-Immune Cell Crosstalk and Related Galectin Secretion by DP3-5 Galacto-Oligosaccharides and β-3′Galactosyllactose

Prebiotic galacto-oligosaccharides (GOS) were shown to support mucosal immune development by enhancing regulatory-type Th1 immune polarization induced by synthetic CpG oligodeoxynucleotides (TLR9 agonist mimicking a bacterial DNA trigger). Epithelial-derived galectin-9 was associated with these immu...

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Bibliographic Details
Main Authors: Veronica Ayechu-Muruzabal, Melanie van de Kaa, Reshmi Mukherjee, Johan Garssen, Bernd Stahl, Roland J. Pieters, Belinda van’t Land, Aletta D. Kraneveld, Linette E. M. Willemsen
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Biomolecules
Subjects:
galacto-oligosaccharides
galectins
intestinal epithelial cells
β-3′galactosyllactose
immunomodulation
mucosal immunity
Online Access:https://www.mdpi.com/2218-273X/12/3/384

Internet

https://www.mdpi.com/2218-273X/12/3/384

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