Blocking the functional domain of TIP1 by antibodies sensitizes cancer to radiation therapy

Blocking the functional domain of TIP1 by antibodies sensitizes cancer to radiation therapy

Non-small-cell lung cancer (NSCLC) and glioblastoma (GB) have poor prognoses. Discovery of new molecular targets is needed to improve therapy. Tax interacting protein 1 (TIP1), which plays a role in cancer progression, is overexpressed and radiation-inducible in NSCLC and GB. We evaluated the effect...

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Bibliographic Details
Main Authors: Abhay K. Singh, David YA Dadey, Michael J. Rau, James Fitzpatrick, Harendra K. Shah, Minakshi Saikia, Reid Townsend, Dinesh Thotala, Dennis E. Hallahan, Vaishali Kapoor
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Radiation therapy
Therapeutic target
Antibody
Lung cancer
Glioblastoma
TIP1
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332223011320

Internet

http://www.sciencedirect.com/science/article/pii/S0753332223011320

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