PHENOTYPIC CHARACTERISATION OF PERIPHERAL BLOOD CYTOTOXIC T LYMPHOCYTES: REGULATORY AND EFFECTOR MOLECULES

PHENOTYPIC CHARACTERISATION OF PERIPHERAL BLOOD CYTOTOXIC T LYMPHOCYTES: REGULATORY AND EFFECTOR MOLECULES

Cytotoxic T lymphocytes (CD3+CD8+, Tcyt) play a major role in protective immunity against intracellular pathogens and can eradicate malignant cells. As based on CD45RA and CD62L expression, the peripheral CD3+CD8+ blood lymphocytes were divided into "na ve" (N) cells, central memory (CM) a...

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Bibliographic Details
Main Authors: I. V. Kudryavtsev, A. G. Borisov, E. V. Vasilyeva, I. I. Krobinets, A. A. Savchenko, M. K. Serebriakova, A. Totolian Areg
Format: Article
Language:Russian
Published: St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists 2018-03-01
Series:Медицинская иммунология
Subjects:
flow cytometry
multicolor immunophenotyping
cytotoxic t cell subsets
cd3+cd8+ maturation
effector molecules
inhibitory receptors
Online Access:https://www.mimmun.ru/mimmun/article/view/1485

Internet

https://www.mimmun.ru/mimmun/article/view/1485

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