Redesigning regulatory components of quorum-sensing system for diverse metabolic control

Existing quorum sensing (QS) circuits are less sophisticated for regulating multiple sets of genes or operons. Here, the authors redesign the luxR-luxI intergenic sequence of the lux-type QS system and apply it to achieve diverse metabolic control in salicylic acid and 4-hydroxycoumarin biosynthesis...

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Bibliographic Details
Main Authors: Chang Ge, Zheng Yu, Huakang Sheng, Xiaolin Shen, Xinxiao Sun, Yifei Zhang, Yajun Yan, Jia Wang, Qipeng Yuan
Format: Article
Language:English
Published: Nature Portfolio 2022-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-29933-x