TSG-6 secreted by human adipose tissue-derived mesenchymal stem cells ameliorates severe acute pancreatitis via ER stress downregulation in mice

TSG-6 secreted by human adipose tissue-derived mesenchymal stem cells ameliorates severe acute pancreatitis via ER stress downregulation in mice

Abstract Background Through recent studies, the onset of acute pancreatitis in pancreatic acinar cells (PACs) and the regulatory role of PACs in severe acute pancreatitis (SAP) have been revealed. During the early stages of pancreatitis, the endoplasmic reticulum (ER) in PACs undergoes significant c...

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Bibliographic Details
Main Authors: Qiang Li, Woo-Jin Song, Min-Ok Ryu, Aryung Nam, Ju-Hyun An, Jin-Ok Ahn, Dong Ha Bhang, Yun Chan Jung, Hwa-Young Youn
Format: Article
Language:English
Published: BMC 2018-09-01
Series:Stem Cell Research & Therapy
Subjects:
Mesenchymal stem cells
Endoplasmic reticulum stress
NF-κB
TSG-6
Severe acute pancreatitis
Online Access:http://link.springer.com/article/10.1186/s13287-018-1009-8

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http://link.springer.com/article/10.1186/s13287-018-1009-8

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