Compartmentalized Replication of SARS-Cov-2 in Upper vs. Lower Respiratory Tract Assessed by Whole Genome Quasispecies Analysis

Compartmentalized Replication of SARS-Cov-2 in Upper vs. Lower Respiratory Tract Assessed by Whole Genome Quasispecies Analysis

We report whole-genome and intra-host variability of SARS-Cov-2 assessed by next generation sequencing (NGS) in upper (URT) and lower respiratory tract (LRT) from COVID-19 patients. The aim was to identify possible tissue-specific patterns and signatures of variant selection for each respiratory com...

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Bibliographic Details
Main Authors: Martina Rueca, Barbara Bartolini, Cesare Ernesto Maria Gruber, Antonio Piralla, Fausto Baldanti, Emanuela Giombini, Francesco Messina, Luisa Marchioni, Giuseppe Ippolito, Antonino Di Caro, Maria Rosaria Capobianchi
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Microorganisms
Subjects:
coronavirus
variability
SARS-COV-2
COVID-19
quasispecies
Online Access:https://www.mdpi.com/2076-2607/8/9/1302

Internet

https://www.mdpi.com/2076-2607/8/9/1302

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