CTHRC1 Induces Pancreatic Stellate Cells (PSCs) into Myofibroblast-like Cancer-Associated Fibroblasts (myCAFs)

CTHRC1 Induces Pancreatic Stellate Cells (PSCs) into Myofibroblast-like Cancer-Associated Fibroblasts (myCAFs)

<b>[BACKGROUND]</b> Collagen triple helix repeat containing-1 (CTHRC1) is a secreted protein that contributes to the progression of various cancers, including pancreatic cancer. The higher expression of CTHRC1 in tumor tissues is associated with poorer survival outcomes. However, its spe...

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Bibliographic Details
Main Authors: Min Kyung Kang, Fen Jiang, Ye Ji Kim, Kyoungjin Ryu, Atsushi Masamune, Shin Hamada, Yun-Yong Park, Sang Seok Koh
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Cancers
Subjects:
cancer-associated fibroblast
cell differentiation
CTHRC1
extracellular matrix
microenvironment myofibroblast
neoplasm metastasis
Online Access:https://www.mdpi.com/2072-6694/15/13/3370

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https://www.mdpi.com/2072-6694/15/13/3370

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