Identification of Novel <i>phoP-phoQ</i> Regulated Genes that Contribute to Polymyxin B Tolerance in <i>Pseudomonas aeruginosa</i>

Identification of Novel <i>phoP-phoQ</i> Regulated Genes that Contribute to Polymyxin B Tolerance in <i>Pseudomonas aeruginosa</i>

Polymyxin B and E (colistin) are the last resorts to treat multidrug-resistant Gram-negative pathogens. <i>Pseudomonas aeruginosa</i> is intrinsically resistant to a variety of antibiotics. The PhoP-PhoQ two-component regulatory system contributes to the resistance to polymyxins by regul...

Full description

Bibliographic Details
Main Authors: Baopeng Yang, Chang Liu, Xiaolei Pan, Weixin Fu, Zheng Fan, Yongxin Jin, Fang Bai, Zhihui Cheng, Weihui Wu
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Microorganisms
Subjects:
polymyxin B
<i>Pseudomonas aeruginosa</i>
PhoP-PhoQ
membrane integrity
Online Access:https://www.mdpi.com/2076-2607/9/2/344

Internet

https://www.mdpi.com/2076-2607/9/2/344

Similar Items