Sepsis-induced changes in pyruvate metabolism: insights and potential therapeutic approaches
Abstract Sepsis is a heterogeneous syndrome resulting from a dysregulated host response to infection. It is considered as a global major health priority. Sepsis is characterized by significant metabolic perturbations, leading to increased circulating metabolites such as lactate. In mammals, pyruvate...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Springer Nature
2024-10-01
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Series: | EMBO Molecular Medicine |
Subjects: | |
Online Access: | https://doi.org/10.1038/s44321-024-00155-6 |