Effect of Double Mutation (L452R and E484Q) on the Binding Affinity of Monoclonal Antibodies (mAbs) against the RBD—A Target for Vaccine Development

The COVID-19 pandemic, caused by SARS-CoV-2, emerges as a global health problem, as the viral genome is evolving rapidly to form several variants. Advancement and progress in the development of effective vaccines and neutralizing monoclonal antibodies are promising to combat viral infections. In the...

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Bibliographic Details
Main Authors: Deepali Gupta, Mukesh Kumar, Priyanka Sharma, Trishala Mohan, Amresh Prakash, Renu Kumari, Punit Kaur
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Vaccines
Subjects:
Online Access:https://www.mdpi.com/2076-393X/11/1/23