Cytosolic 5′-Nucleotidase II Is a Sensor of Energy Charge and Oxidative Stress: A Possible Function as Metabolic Regulator

Cytosolic 5′-nucleotidase II (NT5C2) is a highly regulated enzyme involved in the maintenance of intracellular purine and the pyrimidine compound pool. It dephosphorylates mainly IMP and GMP but is also active on AMP. This enzyme is highly expressed in tumors, and its activity correlates with a high...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Rossana Pesi, Simone Allegrini, Francesco Balestri, Mercedes Garcia-Gil, Federico Cividini, Laura Colombaioni, Lars Petter Jordheim, Marcella Camici, Maria Grazia Tozzi
Fformat: Erthygl
Iaith:English
Cyhoeddwyd: MDPI AG 2021-01-01
Cyfres:Cells
Pynciau:
Mynediad Ar-lein:https://www.mdpi.com/2073-4409/10/1/182