Functional complementation of Leishmania (Leishmania) amazonensis AP endonuclease gene (lamap) in Escherichia coli mutant strains challenged with DNA damage agents

Functional complementation of Leishmania (Leishmania) amazonensis AP endonuclease gene (lamap) in Escherichia coli mutant strains challenged with DNA damage agents

During its life cycle Leishmania spp. face several stress conditions that can cause DNA damages. Base Excision Repair plays an important role in DNA maintenance and it is one of the most conserved mechanisms in all living organisms. DNA repair in trypanosomatids has been reported only for Old World...

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Bibliographic Details
Main Authors: Erika Verissimo-Villela, Milene Yoko Kitahara-Oliveira, Ana Beatriz de Bragança dos Reis, Rodolpho Mattos Albano, Alda Maria Da-Cruz, Alexandre Ribeiro Bello
Format: Article
Language:English
Published: Fundação Oswaldo Cruz (FIOCRUZ) 2016-05-01
Series:Memorias do Instituto Oswaldo Cruz
Subjects:
AP endonuclease
Leishmania amazonensis
lamap
Base Excision Repair
DNA repair
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762016000500349&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762016000500349&lng=en&tlng=en

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