Telomerase immortalization of human corneal endothelial cells yields functional hexagonal monolayers.

Telomerase immortalization of human corneal endothelial cells yields functional hexagonal monolayers.

Human corneal endothelial cells (HCEnCs) form a monolayer of hexagonal cells whose main function is to maintain corneal clarity by regulating corneal hydration. HCEnCs are derived from neural crest and are arrested in the post-mitotic state. Thus cell loss due to aging or corneal endothelial disorde...

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Bibliographic Details
Main Authors: Thore Schmedt, Yuming Chen, Tracy T Nguyen, Shimin Li, Joseph A Bonanno, Ula V Jurkunas
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3528758?pdf=render

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http://europepmc.org/articles/PMC3528758?pdf=render

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