Frequency and Clinical Significance of Elevated IgG4 in Rheumatoid Arthritis: A Systematic Review

Frequency and Clinical Significance of Elevated IgG4 in Rheumatoid Arthritis: A Systematic Review

Immunoglobulin (Ig)G4 is a unique protein molecule and its role in autoimmune diseases remains elusive and controversial. Accumulating evidence suggests a pathogenic role of IgG4 in rheumatoid arthritis (RA). Rheumatoid factors (RF) in RA can recognize the Fc domains of IgG4 to form RF-IgG4 immune c...

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Bibliographic Details
Main Authors: Rajalingham Sakthiswary, Syahrul Sazliyana Shaharir, Asrul Abdul Wahab
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Biomedicines
Subjects:
arthritis
rheumatoid
immunoglobulin G
immune system
Online Access:https://www.mdpi.com/2227-9059/10/3/558

Internet

https://www.mdpi.com/2227-9059/10/3/558

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