Anti-CRISPR Anopheles mosquitoes inhibit gene drive spread under challenging behavioural conditions in large cages

Abstract CRISPR-based gene drives have the potential to spread within populations and are considered as promising vector control tools. A doublesex-targeting gene drive was able to suppress laboratory Anopheles mosquito populations in small and large cages, and it is considered for field application...

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Main Authors: Rocco D’Amato, Chrysanthi Taxiarchi, Marco Galardini, Alessandro Trusso, Roxana L. Minuz, Silvia Grilli, Alastair G. T. Somerville, Dammy Shittu, Ahmad S. Khalil, Roberto Galizi, Andrea Crisanti, Alekos Simoni, Ruth Müller
Format: Article
Jezik:English
Izdano: Nature Portfolio 2024-02-01
Serija:Nature Communications
Online dostop:https://doi.org/10.1038/s41467-024-44907-x