Sterile alpha motif containing 7 (samd7) is a novel crx-regulated transcriptional repressor in the retina.

Inherited retinal diseases are mainly caused by mutations in genes that are highly expressed in photoreceptors of the retina. The majority of these genes is under the control of the transcription factor Cone rod homeobox (Crx), that acts as a master transcription factor in photoreceptors. Using a ge...

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Bibliographic Details
Main Authors: Julia Hlawatsch, Marcus Karlstetter, Alexander Aslanidis, Anika Lückoff, Yana Walczak, Michael Plank, Julia Böck, Thomas Langmann
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3615016?pdf=render