Human iPSC-Derived Retinal Organoids and Retinal Pigment Epithelium for Novel Intronic <i>RPGR</i> Variant Assessment for Therapy Suitability

Human iPSC-Derived Retinal Organoids and Retinal Pigment Epithelium for Novel Intronic <i>RPGR</i> Variant Assessment for Therapy Suitability

The <i>RPGR</i> gene encodes Retinitis Pigmentosa GTPase Regulator, a known interactor with ciliary proteins, which is involved in maintaining healthy photoreceptor cells. Variants in <i>RPGR</i> are the main contributor to X-linked rod-cone dystrophy (RCD), and <i>RPGR...

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Bibliographic Details
Main Authors:	Fidelle Chahine Karam, To Ha Loi, Alan Ma, Benjamin M. Nash, John R. Grigg, Darshan Parekh, Lisa G. Riley, Elizabeth Farnsworth, Bruce Bennetts, Anai Gonzalez-Cordero, Robyn V. Jamieson
Format:	Article
Language:	English
Published:	MDPI AG 2022-03-01
Series:	Journal of Personalized Medicine
Subjects:	<i>RPGR</i> inherited retinal disease rod-cone dystrophy ciliopathy iPSC retinal organoids
Online Access:	https://www.mdpi.com/2075-4426/12/3/502

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