Dynamic Interactions of Post Cleaved NS2B Cofactor and NS3 Protease Identified by Integrative Structural Approaches

Diseases caused by flaviviruses such as dengue virus (DENV) and West Nile Virus (WNV), are a serious threat to public health. The flavivirus single-stranded RNA genome is translated into a polyprotein which is cleaved into three structural proteins and seven non-structural proteins by the viral and...

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Bibliographic Details
Main Authors: Jun-Ping Quek, Zheng Ser, Bing Liang Alvin Chew, Xin Li, Lili Wang, Radoslaw M. Sobota, Dahai Luo, Wint Wint Phoo
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/14/7/1440