Proliferative epithelial changes in tumour adjacent tissue in Sri Lankan women with breast carcinoma: do morphological changes support molecular models of breast carcinogenesis?

Abstract Background The multistep molecular model of breast carcinogenesis is based on the oestrogen receptor(ER) status of the tumour. Its two main arms comprise ER-positive and ER-negative breast carcinomas(BCa), which are associated with Nottingham grade(NG) of the tumour and different proliferat...

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Bibliographic Details
Main Authors: Indumini Maheshika Jinadasa, Harshima Disvini Wijesinghe, Modini Manohari Abeydera Jayawickrama, Menaka Dilani Samarawickrama Lokuhetty
Format: Article
Language:English
Published: BMC 2022-12-01
Series:Diagnostic Pathology
Subjects:
Online Access:https://doi.org/10.1186/s13000-022-01281-w