Expression and Role of Gonadotropin-Releasing Hormone 2 and Its Receptor in Mammals

Expression and Role of Gonadotropin-Releasing Hormone 2 and Its Receptor in Mammals

Gonadotropin-releasing hormone 1 (GnRH1) and its receptor (GnRHR1) drive mammalian reproduction via regulation of the gonadotropins. Yet, a second form of GnRH (GnRH2) and its receptor (GnRHR2) also exist in mammals. GnRH2 has been completely conserved throughout 500 million years of evolution, sign...

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Bibliographic Details
Main Authors: Amy T. Desaulniers, Rebecca A. Cederberg, Clay A. Lents, Brett R. White
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-12-01
Series:Frontiers in Endocrinology
Subjects:
GnRH2
GnRH2 receptor
reproductive function
G protein-coupled receptor
G protein-coupled receptor signal transduction
autocrine/paracrine mechanisms
Online Access:http://journal.frontiersin.org/article/10.3389/fendo.2017.00269/full

Internet

http://journal.frontiersin.org/article/10.3389/fendo.2017.00269/full

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