Disentangling PTEN-cooperating tumor suppressor gene networks in cancer

We have recently performed a whole-body, genome-wide screen in mice using a single-copy inactivating transposon for the identification of Pten (phosphatase and tensin homolog)-cooperating tumor suppressor genes (TSGs). We identified known and putative TSGs in multiple cancer types and validated the...

Full description

Bibliographic Details
Main Authors: Jorge de la Rosa, Julia Weber, Roland Rad, Allan Bradley, Juan Cadiñanos
Format: Article
Language:English
Published: Taylor & Francis Group 2017-07-01
Series:Molecular & Cellular Oncology
Subjects:
Online Access:http://dx.doi.org/10.1080/23723556.2017.1325550