Identification of the Transcriptional Regulatory Role of RUNX2 by Network Analysis in Lung Cancer Cells

Identification of the Transcriptional Regulatory Role of RUNX2 by Network Analysis in Lung Cancer Cells

The use of a new bioinformatics pipeline allowed the identification of deregulated transcription factors (TFs) coexpressed in lung cancer that could become biomarkers of tumor establishment and progression. A gene regulatory network (GRN) of lung cancer was created with the normalized gene expressio...

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Bibliographic Details
Main Authors: Beatriz Andrea Otálora-Otálora, Cristian González Prieto, Lucia Guerrero, Camila Bernal-Forigua, Martin Montecino, Alejandra Cañas, Liliana López-Kleine, Adriana Rojas
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Biomedicines
Subjects:
lung cancer (LC)
differentially expressed genes (DEGs)
transcription factors (TFs)
coexpression networks
gene regulatory network (GRN)
diagnostic and prognostic biomarkers
Online Access:https://www.mdpi.com/2227-9059/10/12/3122

Internet

https://www.mdpi.com/2227-9059/10/12/3122

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