Gα12 and endoplasmic reticulum stress-mediated pyroptosis in a single cycle of dextran sulfate-induced mouse colitis

Gα12 and endoplasmic reticulum stress-mediated pyroptosis in a single cycle of dextran sulfate-induced mouse colitis

Abstract Inflammatory bowel disease (IBD) pathogenesis involves complex inflammatory events and cell death. Although IBD involves mainly necrosis in the digestive tract, pyroptosis has also been recognized. Nonetheless, the underlying basis is elusive. Gα12/13 overexpression may affect endoplasmic r...

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Bibliographic Details
Main Authors: Jihoon Tak, Quanxi An, Sang Gil Lee, Chang Hoon Lee, Sang Geon Kim
Format: Article
Language:English
Published: Nature Portfolio 2024-03-01
Series:Scientific Reports
Subjects:
Gα12/Gα13
ER stress
Pyroptosis
Colitis
Inflammatory bowel disease
Online Access:https://doi.org/10.1038/s41598-024-56685-z

Internet

https://doi.org/10.1038/s41598-024-56685-z

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