Enhanced apoptotic activity of Pluronic F127 polymer-encapsulated chlorogenic acid nanoparticles through the PI3K/Akt/mTOR signaling pathway in liver cancer cells and in vivo toxicity studies in zebrafish

Enhanced apoptotic activity of Pluronic F127 polymer-encapsulated chlorogenic acid nanoparticles through the PI3K/Akt/mTOR signaling pathway in liver cancer cells and in vivo toxicity studies in zebrafish

In this study, chlorogenic acid nanoparticles encapsulated in Pluronic F127 polymer were synthesized and characterized to determine if they could treat human liver cancer. The nanoparticles were synthesized using standard procedures and characterized using physical and biological techniques such as...

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Bibliographic Details
Main Authors: Alanazi Fehaid, Elderdery Abozer Y., Alzahrani Badr, Alzerwi Nasser A. N., Althobiti Maryam Musleh, Rayzah Musaed, Alanazi Abdulaziz Suailem, Kuriri Fahd A., Idrees Bandar, Alenazy Fawaz O., Alsultan Afnan, Rayzah Fares, Baksh Yaser, Subbiah Suresh Kumar, Mok Pooi Ling
Format: Article
Language:English
Published: De Gruyter 2023-11-01
Series:e-Polymers
Subjects:
pluronic f127
chlorogenic acid nanoparticles
hepg2 cell lines
pi3k/akt
mtor pathways
Online Access:https://doi.org/10.1515/epoly-2023-0053

Internet

https://doi.org/10.1515/epoly-2023-0053

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