Exome Sequencing Identifies Susceptibility Loci for Sarcoidosis Prognosis

Exome Sequencing Identifies Susceptibility Loci for Sarcoidosis Prognosis

Many sarcoidosis-associating immunological genes have been shown to be shared between other immune-mediated diseases. In Finnish sarcoidosis patients, good prognosis subjects more commonly have HLA-DRB1*03:01 and/or HLA-DRB1*04:01-DPB1*04:01 haplotype, but no marker for persistent disease have been...

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Bibliographic Details
Main Authors: Elisa Lahtela, Matti Kankainen, Juha Sinisalo, Olof Selroos, Marja-Liisa Lokki
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-12-01
Series:Frontiers in Immunology
Subjects:
sarcoidosis
prognosis
MHC
whole exome sequencing
1p36.21
leucocyte receptor complex
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02964/full

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https://www.frontiersin.org/article/10.3389/fimmu.2019.02964/full

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