An evaluation of circulating activated TAFI in septic DIC: a case series and review of the literature

Abstract Background Administration of recombinant human soluble thrombomodulin (rTM) is often used in Japan to treat septic disseminated intravascular coagulation (DIC). Thrombin-activatable fibrinolysis inhibitor (TAFI) is a fibrinolysis inhibitor activated by the thrombin-thrombomodulin complex, h...

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Bibliographic Details
Main Authors: Takaaki Totoki, Takashi Ito, Midori Kakuuchi, Nozomi Yashima, Ikuro Maruyama, Yasuyuki Kakihana
Format: Article
Language:English
Published: BMC 2022-02-01
Series:Thrombosis Journal
Subjects:
Online Access:https://doi.org/10.1186/s12959-022-00364-4