Synthesis and biochemical characterization of EGF receptor in a water-soluble membrane model system.

Synthesis and biochemical characterization of EGF receptor in a water-soluble membrane model system.

ErbB (Erythroblastic Leukemia Viral Oncogene Homolog) receptor tyrosine kinases are critical for tissue development and maintenance, and frequently become oncogenic when mutated or overexpressed. In vitro analysis of ErbB receptor kinases can be difficult because of their large size and poor water s...

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Bibliographic Details
Main Authors: Tiffany M Scharadin, Wei He, Yianni Yiannakou, Alexey A Tomilov, Matthew Saldana, Gino A Cortopassi, Kermit L Carraway, Matthew A Coleman, Paul T Henderson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5460842?pdf=render

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http://europepmc.org/articles/PMC5460842?pdf=render

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