Azithromycin and Sildenafil May Have Protective Effects on Retinal Ganglion Cells via Different Pathways: Study in a Rodent Microbead Model

Azithromycin and Sildenafil May Have Protective Effects on Retinal Ganglion Cells via Different Pathways: Study in a Rodent Microbead Model

Decreased blood flow to the optic nerve (ON) and neuroinflammation are suggested to play an important role in the pathophysiology of glaucoma. This study investigated the potential neuroprotective effect of azithromycin, an anti-inflammatory macrolide, and sildenafil, a selective phosphodiesterase-5...

Full description

Bibliographic Details
Main Authors: Tal Corina Sela, Alon Zahavi, Moran Friedman-Gohas, Shirel Weiss, Amir Sternfeld, Astrid Ilguisonis, Danielle Badash, Noa Geffen, Ron Ofri, Yaniv BarKana, Nitza Goldenberg-Cohen
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Pharmaceuticals
Subjects:
glaucoma
microbeads
neuroprotection
sildenafil
azithromycin
Online Access:https://www.mdpi.com/1424-8247/16/4/486

Internet

https://www.mdpi.com/1424-8247/16/4/486

Similar Items