Intravenous vitamin C monotherapy in critically ill patients: a systematic review and meta-analysis of randomized controlled trials with trial sequential analysis

Intravenous vitamin C monotherapy in critically ill patients: a systematic review and meta-analysis of randomized controlled trials with trial sequential analysis

Abstract Background A recent landmark randomized controlled trial (RCT) in septic patients demonstrated an increased risk of death and persistent organ dysfunction with intravenous Vitamin C (IVVC) monotherapy, which represents a disparate result from previous systematic reviews and meta-analyses (S...

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Bibliographic Details
Main Authors: Zheng-Yii Lee, Luis Ortiz-Reyes, Charles Chin Han Lew, M. Shahnaz Hasan, Lu Ke, Jayshil J. Patel, Christian Stoppe, Daren K. Heyland
Format: Article
Language:English
Published: SpringerOpen 2023-03-01
Series:Annals of Intensive Care
Subjects:
Vitamin C
Ascorbic acids
Sepsis
Critical illness
Systematic review
Online Access:https://doi.org/10.1186/s13613-023-01116-x

Internet

https://doi.org/10.1186/s13613-023-01116-x

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