Inflammatory priming with IL-1β promotes the immunomodulatory behavior of adipose derived stem cells

Inflammatory priming with IL-1β promotes the immunomodulatory behavior of adipose derived stem cells

Inflammatory processes contribute to osteoarthritis (OA) severity and progression. Mesenchymal stem cells, particularly those derived from adipose tissue (ASCs), are able to sense and control the inflammatory environment. This immunomodulatory potential can be boosted by different priming strategies...

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Bibliographic Details
Main Authors: Alessandra Colombini, Francesca Libonati, Davide Cangelosi, Silvia Lopa, Paola De Luca, Domenico Antonio Coviello, Matteo Moretti, Laura de Girolamo
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
adipose derived stem cells
early osteoarthritis
interleukin 1 beta
inflammatory priming
immunomodulation
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2022.1000879/full

Internet

https://www.frontiersin.org/articles/10.3389/fbioe.2022.1000879/full

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