In situ generation of micrometer-sized tumor cell-derived vesicles as autologous cancer vaccines for boosting systemic immune responses
Autologous tumor cell vaccines can elicit anti-tumor immune responses. Here, the authors report the design of dendritic polymer-based nanoparticles loaded with doxorubicin and the tyrosine kinase inhibitor apatinib that can induce immunogenic cell death and the in situ production of immuno-stimulato...
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Bibliographic Details
| Main Authors: |
Yuxin Guo,
Shao-Zhe Wang,
Xinping Zhang,
Hao-Ran Jia,
Ya-Xuan Zhu,
Xiaodong Zhang,
Ge Gao,
Yao-Wen Jiang,
Chengcheng Li,
Xiaokai Chen,
Shun-Yu Wu,
Yi Liu,
Fu-Gen Wu |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Portfolio
2022-11-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/s41467-022-33831-7
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