Statistical analysis of crystallization database links protein physico-chemical features with crystallization mechanisms.

X-ray crystallography is the predominant method for obtaining atomic-scale information about biological macromolecules. Despite the success of the technique, obtaining well diffracting crystals still critically limits going from protein to structure. In practice, the crystallization process proceeds...

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Bibliographic Details
Main Authors: Diana Fusco, Timothy J Barnum, Andrew E Bruno, Joseph R Luft, Edward H Snell, Sayan Mukherjee, Patrick Charbonneau
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4079662?pdf=render