Prednisolone as preservation additive prevents from ischemia reperfusion injury in a rat model of orthotopic lung transplantation.

The lung is, more than other solid organs, susceptible for ischemia reperfusion injury after orthotopic transplantation. Corticosteroids are known to potently suppress pro-inflammatory processes when given in the post-operative setting or during rejection episodes. Whereas their use has been approve...

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Bibliographic Details
Main Authors: Patrick Paulus, Johannes Holfeld, Anja Urbschat, Haitham Mutlak, Pia Alexandra Ockelmann, Sabine Tacke, Kai Zacharowski, Christin Reissig, David Stay, Bertram Scheller
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3756949?pdf=render