Reduced-dose WBRT combined with SRS for 1–4 brain metastases aiming at minimizing neurocognitive function deterioration without compromising brain tumor control

Reduced-dose WBRT combined with SRS for 1–4 brain metastases aiming at minimizing neurocognitive function deterioration without compromising brain tumor control

Background and purpose: To minimize cognitive decline without increasing brain tumor recurrence (BTR) by reduced-dose whole-brain radiotherapy (RD-WBRT) (25 Gy, 10 fractions) + stereotactic radiosurgery (SRS) in patients with ≤ 4 brain metastases. Materials and methods: Eligible patients with ≤ 4 br...

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Bibliographic Details
Main Authors: Toshimichi Nakano, Hidefumi Aoyama, Shunsuke Onodera, Hiroshi Igaki, Yasuo Matsumoto, Ayae Kanemoto, Shigetoshi Shimamoto, Masayuki Matsuo, Hidekazu Tanaka, Natsuo Oya, Tomohiko Matsuyama, Atsushi Ohta, Katsuya Maruyama, Takahiro Tanaka, Nobutaka Kitamura, Kohei Akazawa, Katsuya Maebayashi
Format: Article
Language:English
Published: Elsevier 2022-11-01
Series:Clinical and Translational Radiation Oncology
Subjects:
Brain metastases
Cognition
Recurrence
Radiation
Whole brain
Stereotactic radiosurgery
Online Access:http://www.sciencedirect.com/science/article/pii/S2405630822000805

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http://www.sciencedirect.com/science/article/pii/S2405630822000805

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