PRRSV Induces HMGB1 Phosphorylation at Threonine-51 Residue to Enhance Its Secretion

Porcine reproductive and respiratory syndrome virus (PRRSV) induces secretion of high mobility group box 1 (HMGB1) to mediate inflammatory response that is involved in the pulmonary injury of infected pigs. Our previous study indicates that protein kinase C-delta (PKC-delta) is essential for HMGB1 s...

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Bibliographic Details
Main Authors: Rong Wang, Jingyi Zhang, Yu Fu, Linying Jia, Yali Zhang, Liang Bai, Weirong Wang, Daxin Cheng, Enqi Liu
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/14/5/1002