T-cell count and T-cell telomere length in patients with severe COVID-19

T-cell count and T-cell telomere length in patients with severe COVID-19

Lymphocyte telomere length (TL) is highly variable and shortens with age. Short telomeres may impede TL-dependent T-cell clonal expansion with viral infection. As SARS-CoV-2 infection can induce prolonged and severe T-cell lymphopenia, infected adults, and particularly older adults with short telome...

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Bibliographic Details
Main Authors: Bryan D. Kraft, Simon Verhulst, Tsung-Po Lai, Bruce A. Sullenger, Yunfei Wang, Wes Rountree, Lingye Chen, Christopher W. Woods, Thomas N. Denny, Abraham Aviv
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Immunology
Subjects:
SARS-CoV-2
COVID-19
T-lymphocytes
lymphopenia
sex
aging
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1356638/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2024.1356638/full

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