Pre-treatment with candesartan protects from cerebral ischaemia
Angiotensin II (Ang II) regulates cerebral blood flow by stimulating cerebral vasoconstriction via AT 1 receptors. In adult spontaneously hypertensive rats (SHR), the cerebrovascular autoregulatory curve is shifted to the right, in the direction of higher blood pressures, an indication of excessive...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
SAGE Publications
2001-09-01
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Series: | Journal of the Renin-Angiotensin-Aldosterone System |
Online Access: | https://doi.org/10.3317/jraas.2001.024 |