Strain-level resolution and pneumococcal carriage dynamics by single-molecule real-time (SMRT) sequencing of the plyNCR marker: a longitudinal study in Swiss infants

Strain-level resolution and pneumococcal carriage dynamics by single-molecule real-time (SMRT) sequencing of the plyNCR marker: a longitudinal study in Swiss infants

Abstract Background Pneumococcal carriage has often been studied from a serotype perspective; however, little is known about the strain-specific carriage and inter-strain interactions. Here, we examined the strain-level carriage and co-colonization dynamics of Streptococcus pneumoniae in a Swiss bir...

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Bibliographic Details
Main Authors: Oluwaseun Rume-Abiola Oyewole, Philipp Latzin, Silvio D. Brugger, Markus Hilty
Format: Article
Language:English
Published: BMC 2022-09-01
Series:Microbiome
Subjects:
Respiratory microbiome
PacBio single-molecule real-time (SMRT) sequencing
DADA2
Co-colonization
Streptococcus pneumoniae
Carriage duration
Online Access:https://doi.org/10.1186/s40168-022-01344-6

Internet

https://doi.org/10.1186/s40168-022-01344-6

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